Why was a meta-analysis performed with primary endpoints considered clinically unimportant?

Letter to the Editor accepted in AOGS regarding the latest Meta Analysis:

Why did the authors perform a meta-analysis of studies with primary endpoints they consider clinically unimportant?

Kessler et al. 2016
DOI: 10.1111/aogs.12876

 

ABSTRACT
The meta-analysis of Blix et al. on ST waveform analysis (STAN) (1) confirmed the results of a previous meta-analysis (2). Their conclusions, however, are based on presuppositions that are highly questionable. The systematic review by Blix et al. (1) was prompted by a recently published American RCT on STAN (3) However, this RCT was performed on a predominantly low-risk population with guidelines for CTG interpretation and threshold for STAN intervention different from those applied in all European RCTs and in clinical use. Furthermore, the experience of the health workers with STAN in this trial must have been minimal beyond the pre-trial courses.

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